Severe Periocular Comedonal Acne and Inflamed Epidermoid Cyst: A Clinical Overview ( video below )

Skin lesions around the eyes are particularly concerning because the periocular area is one of the most delicate and sensitive regions of the face. The image above demonstrates a combination of multiple open comedones (blackheads), closed comedones (whiteheads), milia-like lesions, and a large inflamed cystic lesion located near the lower eyelid and upper cheek. This presentation reflects a chronic follicular disorder complicated by secondary inflammation, and it highlights the importance of proper dermatologic assessment and management.

Understanding the Periocular Skin

The skin around the eyes differs from other facial areas in several important ways:

  • It is thinner and more fragile

  • It contains fewer oil glands

  • It is more prone to irritation, swelling, and scarring

  • It is located close to vital structures such as the eye, tear ducts, and nerves

Because of these characteristics, even relatively common skin conditions can become complicated or risky if improperly treated.

Key Lesions Visible in the Image

1. Open Comedones (Blackheads)

Multiple dark, circular plugs are visible clustered beneath the lower eyelid. These are open comedones, commonly known as blackheads.

How they form:

  • Dead skin cells and sebum accumulate inside hair follicles

  • The follicle opening remains open

  • Oxidation of keratin and oil causes the dark coloration

Why they appear periocularly:

  • Chronic sun damage

  • Aging skin

  • Long-term use of heavy cosmetics

  • Poor cleansing or occlusive products

  • Certain genetic skin types

2. Closed Comedones and Milia-like Lesions

Small, pale, dome-shaped bumps are also visible around the area.

These may represent:

  • Closed comedones (whiteheads)

  • Milia, which are keratin-filled cysts trapped beneath the skin surface

These lesions are common around the eyes because:

  • The skin exfoliates more slowly

  • Products can easily become trapped

  • The area is often avoided during cleansing

3. Inflamed Epidermoid (Sebaceous) Cyst

The most prominent lesion is a large, swollen, pink-to-red nodule with a visible central point and evidence of medical intervention (a suture).

This lesion is consistent with an inflamed epidermoid cyst, sometimes incorrectly called a “sebaceous cyst.”

Characteristics include:

  • Firm or fluctuant swelling

  • Redness and tenderness

  • Central punctum (blocked follicular opening)

  • Risk of infection if ruptured

Inflammation occurs when:

  • The cyst wall ruptures

  • Keratin contents spill into surrounding tissue

  • The immune system triggers a strong inflammatory response

Why This Combination Occurs

This type of presentation often results from long-standing follicular blockage combined with poor drainage and chronic irritation.

Contributing factors may include:

  • Thick or oily skin texture

  • Aging-related changes in skin turnover

  • Sun exposure

  • Use of occlusive eye creams or makeup

  • Repeated manipulation or squeezing

  • Underlying acne-prone skin

Over time, untreated comedones can progress into larger cystic lesions, especially when bacteria and inflammation become involved.

Medical Management and Treatment Approaches

1. Professional Extraction

Due to the proximity to the eye:

  • Manual extraction should only be performed by trained professionals

  • Improper squeezing can cause:

    • Infection

    • Scarring

    • Spread of inflammation

    • Damage to nearby structures

2. Cyst Treatment

Inflamed cysts near the eye often require:

  • Sterile drainage

  • Possible suturing

  • Anti-inflammatory treatment

  • Monitoring for infection

Self-treatment at home is strongly discouraged.

3. Topical Therapies (Under Medical Supervision)

Possible options include:

  • Mild retinoids formulated for periocular use

  • Keratolytic agents in very low concentrations

  • Non-comedogenic moisturizers

  • Targeted antibiotic or anti-inflammatory treatments if needed

4. Prevention Strategies

Long-term management focuses on preventing recurrence:

  • Use lightweight, non-comedogenic eye products

  • Cleanse gently but consistently

  • Avoid heavy oils near the eyes

  • Do not squeeze or pick lesions

  • Protect skin from sun damage

  • Schedule regular dermatologic evaluations if prone to comedones

Risks of Ignoring or Mismanaging Periocular Lesions

Failure to properly treat lesions in this area can lead to:

  • Persistent inflammation

  • Permanent scarring

  • Post-inflammatory hyperpigmentation

  • Recurrent cyst formation

  • Functional or cosmetic concerns

Early intervention significantly improves outcomes and reduces complications.

When to See a Dermatologist

Seek professional care if:

  • Lesions increase in size or number

  • Swelling or redness worsens

  • Pain or tenderness develops

  • Lesions recur after treatment

  • Vision is affected or discomfort occurs near the eye

Conclusion

The image illustrates a complex periocular skin condition involving multiple comedones and an inflamed epidermoid cyst, emphasizing the importance of specialized care in sensitive facial areas. While these lesions may appear similar to common acne, their location and severity require a cautious, medically guided approach.

Proper diagnosis, professional treatment, and preventive skincare are essential to protect both the health of the skin and the structures surrounding the eye. Early care not only improves appearance but also prevents long-term complications.